This was found as the result of rummaging through the back issues (June 23 2007) of New Scientist magazine. An article on nanobacteria tells of what most of us had never heard or read of before. Not surprisingly, there are issued and pending patents, probably with more to come. Maybe a growing practice area of biotech patent lawyers. A few paragraphs:
The Medusa Strain - an unknown life form is hardening your
arteries and turning your kidneys to stone. That's if it
exists at all
- by Bijal Trivedi, New Scientist, 23 June 2007, 38
THEY are minuscule egg-shaped structures mere billionths of a metre
across, dwarfed by the tiniest living cell and smaller than many
viruses. They have a hard bony shell, replicate like a living
organism and are wiped out by antibiotics and radiation, yet seem
to lack DNA. Some say they are infectious microbes, possibly even
an unknown form of life, able to cause diseases ranging from
Alzheimer's to atherosclerosis. Others say they are simply
harmless crystals.
Welcome to the topsy-turvy world of nanobacteria. Once described as
the "cold fusion of microbiology", the very existence of these
microbes has been denied or ridiculed by mainstream opinion for
nearly a decade and their proponents branded mavericks. Just like
cold fusion, though, nanobacteria have refused to go away and now
- under the new guise of "calcifying nanoparticles" - they are making
a renewed bid for scientific respectability. The stakes are high. If
diseases long thought incurable are actually caused by nanobacteria,
they could be prevented with vaccines, or treated with antibiotics.
A recent patent application is typical:
United States Patent Application 20070134814
Methods and compositions for the detection of calcifying
nano-particles, identification and quantification of associated
proteins thereon, and correlation to disease
Abstract
Disclosed are methods and compositions for detecting, analyzing
and assessing the significance of calcifying nano-particles. The
disclosed methods and compositions generally involve detecting one
or more proteins present on a calcifying nano-particle. It has been
discovered that particular proteins become associated with calcifying
nano-particles. This association provides a means for detecting,
classifying, analyzing, categorizing, and assessing calcifying
nano-particles. Detecting particular proteins while associated with
a calcifying nano-particle can be used to indicate the presence and
type of calcifying nano-particle, which can be used to indicate the
presence of, or disposition to, diseases or conditions. Multiple
proteins on a calcifying particle can be detected. The presence or
absence of particular proteins and the pattern of the presence and
absence of particular proteins can be used to indicate the presence
and type of calcifying nano-particle.
Friday, June 20, 2008
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